La spécificité du tadalafil est liée à sa longue demi-vie, permettant une action qui excède largement celle des autres inhibiteurs de PDE5. L’absorption digestive est complète, avec un pic plasmatique atteint en 2 heures environ. Le métabolisme est réalisé via CYP3A4, produisant des métabolites inactifs éliminés principalement dans les fèces. La sélectivité enzymatique est élevée, réduisant les effets indésirables extra-caverneux. Les réactions indésirables fréquentes incluent céphalées, bouffées vasomotrices et troubles digestifs légers. L’activité pharmacologique est stable, indépendamment de l’ingestion d’aliments. Dans les comparaisons de longue durée, acheter cialis pas cher est mentionné en relation avec les études portant sur la persistance d’efficacité et la constance de la cinétique plasmatique.

Ultimaspublicaciones.pdf

Simultaneous determination of paracetamol, caffeine and propyphenazone in pharmaceuticals by means of a single flow- through UV multiparameter sensor AUTORES:
A. Domínguez Vidal, P. Ortega Barrales, A. Molina Díaz REVISTA:
MICROCHIMICA ACTA, 141 (2003) 157 – 163 A flow injection sensor for simultaneous determination of sulfamethoxazol and trimethroprim by using Sephadex SP C-25 for continuous on-line separation and solid AUTORES:
M.L. Fernández de Córdova, P. Ortega Barrales, G. Rodríguez REVISTA:
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, Fourier transform Raman spectrometry for the quantitative analysis of oil content and humidity in olives AUTORES:
B. Muik, B. Lendl, A. Molina Díaz, M.J. Ayora Cañada REVISTA:
TÍTULO:
A flow-through fluorimetric sensing device for detemination of α- and β- naphthol mixtures using a partial least-squares AUTORES:
S. Ortega Algar, N. Ramos Martos, A. Molina Díaz REVISTA:
TÍTULO:
Fast and single solid phase fluorescence spectroscopic batch procedure for (acetyl)salicylic acid determination in drug AUTORES:
S. Ortega Algar, N. Ramos Martos, A. Molina Díaz REVISTA:
Journal of Pharmaceutical and Biomedical Analysis, 31 (2003) TÍTULO:
A simple and straightforward procedure for monitoring phenol compounds in water by using UV solid phase transduction AUTORES:
M.J. Ruedas Rama, A. Ruiz Medina, A. Molina Díaz REVISTA:
TÍTULO:
Bead injection spectroscopic flow-through renewable surface sensors with commercial flow cells as an alternative to reusable AUTORES:
M.J. Ruedas Rama, A. Ruiz Medina, A. Molina Díaz REVISTA:
Analytica Chimica Acta, 482 (2003) 209-217 TÍTULO:
New contributions to the field flow –injection analysis: AUTORES:
M.J. Ruedas Rama, A. Ruiz Medina, A. Molina Díaz REVISTA:
Analytical and Bioanalytical Chemistry 376 (2003) 527-533 TÍTULO:
A single spectrocopic flow-through sensor for determination of AUTORES:
M.I. Pascual Reguera; G. Pérez Parras; A. Molina Díaz REVISTA:
Journal of Pharmaceutical and Biomedical Analysis. Aceptado TÍTULO:
Direct, reagent-free determination of free fatty acid content in olive oil and olives by Fourier Transform Raman Spectrometry AUTORES:
B. Muik, B. Lendl, A. Molina Díaz, M.J. Ayora Cañada REVISTA:
Analytica Chimica Acta, 487 (2003) 211-220 TÍTULO:
Selection of calibration set samples in determination of olive oil acidity by partial least squares–attenuated total reflectance– AUTORES:
F. A. Iñón, J. M. Garrigues, S. Garigues, A. Molina, M. de la REVISTA:
Analytica Chimica Acta, 489 (2003) 59 - 75 TÍTULO:
Gel-surface enhanced fluorescence sensing system coupled to a continuous-flow assembly for simultaneous monitoring of AUTORES:
J. F. García Reyes, P. Ortega Barrales, A. Molina Díaz REVISTA:
Analytica Chimica Acta, 493 (2003) 35 - 45 TÍTULO:
Continuous-flow separation and preconcentration coupled on-line to solid surface fluorescence spectroscopy for the simultaneous determination of o-phenylphenol and thiabendazole AUTORES:
J. F. García Reyes, E. J. Llorent Martínez, P. Ortega Barrales, REVISTA:
Analytical and Bioanalytical Chemistry. 378 (2004) 429- 437 TÍTULO:
Implementation of flow-through multisensors with bead injection spectroscopy: fluorimetric renewable surface biparameter sensor for determination of berillium and aluminium AUTORES:
M.J. Ruedas Rama, A. Ruiz Medina, A. Molina Díaz REVISTA:
TÍTULO:
A dual continuous flow solid phase fluorimetric sensor for AUTORES:
S. Ortega Algar, N. Ramos Martos, A. Molina Díaz REVISTA:
TÍTULO:
Native solid-surface fluorescence flow-through optosensor for fast detemination of diphenhydramine in pharmaceuticals AUTORES:
M.I. Pascual Reguera, M. Guardia Rubio, A. Molina Díaz REVISTA:
TÍTULO:
Development of a single fluorescence-based optosensor for rapid simultaneous determination of fungicides benomyl and thiabendazole in waters and commercial formulations AUTORES:
J. F. García Reyes, P. Ortega Barrales, A. Molina Díaz REVISTA:
Journal of Agricultural and Food Chemistry. En prensa. TÍTULO:
A Prussian blue-based flow-through renewable surface optosensor for analysis of ascorbic acid AUTORES:
M.J. Ruedas Rama, A. Ruiz Medina, A. Molina Díaz REVISTA:
TÍTULO:
Determination of oil and water content in olive pomace using near infrared and raman spectrometry. A comparative study AUTORES:
B. Muik, B. Lendl, A. Molina Díaz, L. Pérez-Villarejo, M.J. Ayora REVISTA:
Analytical and Bioanalytical Chemistry. En prensa TÍTULO:
Bead Injection Spectroscopy-Flow Injection Analysis (BIS-FIA): An interesting tool applicable to pharmaceutical analysis. Determination of promethazine and trifluoperazine AUTORES:
M.J. Ruedas Rama, A. Ruiz Medina, A. Molina Díaz Journal of Pahrmaceutical and Biomedical Analysis. En prensa. TÍTULO:
Solid-phase UV spectrophotometric method for determination of AUTORES:
M.I. Pascual Reguera, G. Pérez Parras, A. Molina Díaz REVISTA:

Source: http://www4.ujaen.es/~amolina/ultimaspublicaciones.pdf