Medical data is for informational purposes only. You should always consult your family physician, or one of our referral physicians prior to treatment.
term and extensive use the benefits of chelates are lost with thenonspecific removal and reduction of the essential trace metals.
Chelation therapy can be a double edge sword like steroid therapythat can help or put the patients at greater risk with the temporarycontrol of symptoms and not the primary causes. The reductionand elimination of arterial plaque formation by dietary and chela-tion means can have life saving benefits but does not, eliminate the suspected infectious and persisting causes. Treatment of vas- The Role of Chelation Therapy: Antibioticsand Mycoplasms
cular disorders of microbial causes such as mycoplasmas and chlamydia with the chelating tetracycline antibiotics can provide (Portions taken from the book Why Arthritis? Searching for the Whether mycoplasmas or other microbes are the per- sistent sensitizing pathogens in collagen vascular disorders remains Submitted by The Arthritis Trust of America, 7376 Walker Road, to be demonstrated. The primary concern is a safer and more ef- Fairview, TN 37062; fective treatment of the toxic forms of therapy that impose a greaterdanger and economic burden. The tetracyclines are potent chelat-ing (eomplexing) medications and as such have been found to actas antiinflammatory, immmosuppressive, and anti-metallic en-zymes as well as antimicrobial. When tetracyclines complex withcopper they become active antioxidants and antiinflammatoryagents (electron scavengers) by neutralizing the damaging oxy-gen free radicals produced by the activated leucocytes. By com-bining with the copper, zinc, iron and other trace metal elementsin enzymes such as collagenase, tetracyclines can inhibit the en-zymatic destruction of tissues. Consequently the mode of tetracy-cline or chelate administration, intravenous or oral, could have apronounced effect on their complexed state and thus their reactiv-ity. Prescribing some medications “Between Meals” or with meals is an attempt to provide optimum conditions for the utilization ofeach drug. Even between meals the gastro-intestinal tract contents Why are some doctors and patients speaking & shout- provide a much greater diversification of chemicals and acidity ing out for Chelation therapy? The recent hearing held in Tampa than the blood. Thus when tolerable the more direct intravenous by a committee of the Florida Board of Medicine attracted pa- administration of tetracyclines and other chelating drugs will be tients and doctors from Florida and across the country. A mix-up more constant and effective than oral medication. The intermit- in scheduled time provoked the president of the Pro-Chelation tent administration or pulse doses, 2-3/week rather than daily is Alliance for Medical Freedom to accuse the committee of being a more effective by giving the tissues time to normalize.
The beneficial effects of tetracyclines and other chelat- What is so special about Chelation therapy that has been ing agents such as EDTA, aspirin, and vitamins C, E, or A, are used and promoted for over 50 years, but never clinically tested in attributed to their metal complex and their resulting multiple ac- chronic diseases? Another similar form of chelation therapy that tions, including antimicrobial. The administration of multiple has been used and promoted for over 50 years is treatment of acting chelating drugs could enhance or inhibit their activity and arthritis with tetracycline antibiotics. The tetracyclines were re- effectiveness depending upon their relative affinity. For example cently clinically tested and found to be safe and effective in rheu- EDTA with a greater affinity for Calcium than tetracyclines could matoid arthritis and the inhibition of metallic enzymes such as have a greater anticoagulant action. On the other hand tetracycline’s collagenase that destroys tissue collagen.
greater affinity for nucleic acids and lipids than most chelates Chelation is a chemical term given to molecules that results in a greater inhibition of protein synthesis and microbial combine or complex with metals such as lead, mercury, copper, growth. It is of interest to note that for many years the combina- iron, calcium, etc. The term is taken from ‘chela’ the pincerlike tion of Vitamin E and Selenium, a metal chelate, was a favorite claws of crabs. Such agents hold metals making them ineffective arthritis medication used by veterinarians. Perhaps Bayer’s plain by limiting their availability for metabolic activity. One such aspirin was touted as faster acting because it was not prechelated chelating agent that is widely used is a synthetic amino acid, eth- and neutralized with less effective metals.
ylene diamine tetra-acetic acid, or EDTA that chelates the toxic Although not accepted clinically perhaps the preformed metals such as lead & mercury, as well as calcium and the other copper-aspirinate would be more effective in the control of essential trace metals. As chelating agents the other amino acids inflamation and the preformed copper-tetracyclinate would con- (protein fragments), vitamins A, C and E, are also used in chela- trol the collagen vascular disorders of microbial origin. In contrast the chelate D-penicillamine medication used to chelate copper and Aspirin and other antinflamatory (NSAIDS) chelates treat rheumatoid arthritis was found to inhibit mycoplasma growth convey a variety of benefits to multiple organ systems. Most no- when complexed with copper. Another aspect of chelation to con- tably by combining with Calcium as an anticoagulant improves sider is the potential adverse or beneficial affects of two or more the cardiovascular and macular degeneration. By reducing arte- chelating medications administered similtaneously. Excesive use rial plaque formation with an increased blood supply relieves pa- of the EDTA or tetracycline chelates could inhibit the copper/zinc tients from angina, claudication, and dizziness. However with long superoxide dismutase enzyme that protects against the tissue de- Medical data is for informational purposes only. You should always consult your family physician, or one of our referral physicians prior to treatment.
struction induced by oxygen free-radicals.
Hopefully in the near future patients and doctors will be shouting out for the safe and effective antibiotic che-lates that will help to eliminate not only the broad symptomsbut also the microbial cause.


Annettes profil

Dr. Annette Olsen Professional qualifications • M.Sc. Biology (Parasitology), University of Copenhagen, 1985 • Ph.D. degree in biology (Parasitology), University of Copenhagen, 1999 • In 2004 evaluated and found qualified as associate professor in epidemiology at the Department of Epidemiology, Institute of Public Health, University of Copenhagen Current position Senior Research

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