La spécificité du tadalafil est liée à sa longue demi-vie, permettant une action qui excède largement celle des autres inhibiteurs de PDE5. L’absorption digestive est complète, avec un pic plasmatique atteint en 2 heures environ. Le métabolisme est réalisé via CYP3A4, produisant des métabolites inactifs éliminés principalement dans les fèces. La sélectivité enzymatique est élevée, réduisant les effets indésirables extra-caverneux. Les réactions indésirables fréquentes incluent céphalées, bouffées vasomotrices et troubles digestifs légers. L’activité pharmacologique est stable, indépendamment de l’ingestion d’aliments. Dans les comparaisons de longue durée, acheter cialis pas cher est mentionné en relation avec les études portant sur la persistance d’efficacité et la constance de la cinétique plasmatique.

Apcmcollege.ac.in

Dr. P. G. Seethalakshmi, M.Sc., M.Phil., Ph.D.,
Principal,
A.P.C. Mahalaxmi College for Women,
Thoothukudi – 628002
ACADEMIC QUALIFICATIONS:

PH.D. THESIS TITLE:
Synthesis and Charecterization of co-crystals of caffeine, DABCO, 4,4’-bipyridine and stien with some organic acidic compounds
EXPERIENCE:
Teaching Experience
Administrative Experience:
 Head of the department of Chemistry from 2002  Chairman of Chemistry UG Practical Board of studies from 2012  Member of Board of Management of A.P.C. Mahalaxmi College from 2011  Member of IQAC of A.P.C. Mahalaxmi College for Women from 2000
PUBLICATIONS:
Total Number of Papers
9 in international journals with impact factor Title of the
Title of the Paper
Acta Crystal
Acta Crystal
carboxypyridine-2-carboxylate)2,17-hydrate Journal of
Molecular
Structure
4,4'-bipyridine-bis(N-phenylanthranilic acid) and 4,4'-bipyridinium bis(3-carboxypyridine-2-carboxylate) Spectrohimica
Acta Part A
3,3'-bis(indolyl)methanes and studies on their spectral characteristics, DPPH radical scavenging, antimicrobial-, cytotoxicity-, and antituberculosis activity Journal of
Molecular
Structure
Syntheses, structural characterization, and biological activity Journal of
Syntheses, structural characterization na Molecular
Structure
Cocrystals of Caffeine with 1- and 2-napthoxyacetic acids Journal of
Molecular
Structure
DPPH radical scavenging activity of the cocrystals caffine:cinnamic acid and caffeine:eosin dehydrate Journal of
Molecular
Structure
scavenging-, Cytotoxicity-, and DFT studies of phenoxyaliphatic acids of 1,8-dioxo-octahydroxanthene derivatives Spectrohimica
Acta Part A
synthese, characterization, Single crystal XCRD, Electronic spectral DPPH radical scavenging and DNA protection studies of aryl-3,3'-bis(indolyl)methanes
PAPERS PRESENTED IN CONFERENCES:
Total Number of Papers Presented
S.No Date
Title of the paper
Institution
“Synthesis and single crystal XRD of an Organic cocrystal “ 4,4’- Bipyridine: N- “Synthesis and crystal structure of a self bis (3-carboxypyridine-2-carboxylate), In the National Conference

PARTICIPATION IN PROGRAMMES:
Total Number of Seminars attended
Total Number of Workshops attended
PROGRAMMES ORGANIZED:
Organized many Regional , State level , and National level Seminars and workshops. POSITIONS HELD:
 In-charge of Fine Arts for ten years  In-charge of Carrer Guidence Cell for five years  In-charge of Humour Club for two years REFRESHER COURSES ATTENDED:
 UGC Refresher course in Chemistry “Applications of Modern Spectroscopic Techniques” from 30.01.2002 to 19.02.2002 conducted by Manonmaniam Sundaranar University  UGC Refresher course in Chemistry “Modern trends in Chemistry” held from 05.11.2003 to 25.11.2003 conducted by V.O.Chidambaram College, Thoothukudi  UGC Refresher course in “Industrial Chemistry” from 16.11.2004 to 06.12.2004
CONTRIBUTION AS RESOURCE PERSON:
 Resource person for the in-service training programme for +2 teachers conducted by Annammal College of Education on 04.01.2005 and 08.01.2005  Resource person for the in-service training programme for High School teachers conducted by A.P.C. Mahalaxmi College for Women on 27.01.2005 and 28.01.2005  Chaired a session in the National Seminar on “Quest for Excellence” organized by IQAC, A.P.C. Mahalaxmi College for Women on 20.08.2009  Chaired a session in the State level Seminar on “Best Practices in Mentoring Students” organized by IQAC, A.P.C. Mahalaxmi College for Women on 04.01.2005

Source: http://www.apcmcollege.ac.in/principal.pdf