ROBIN L. AUPPERLE, PH.D.
5030 Cherry Street, Kansas City, MO 64110
Email: [email protected] Phone: 816-235-5865
EDUCATION
PH.D., UNIVERSITY OF KANSAS, LAWRENCE, KS
Clinical Psychology Dissertation: An fMRI study examining the effects of acute D-cycloserine administration on brain activations and cognitive functioning in spider phobia.
Chair: Douglas Denney, Ph.D. Co-Chair: Cary Savage, Ph.D. Committee: Rick Ingram, Ph.D., John Colombo, Ph.D., Lisa hale, Ph.D.
M. A., UNIVERSITY OF KANSAS, LAWRENCE, KS
Clinical Psychology Thesis: Omega-3 Fatty Acids and Multiple Sclerosis: Examination of the Relationship between Fatty Acids and Depression in MS.
Committee: Sharon Lynch, M.D., Debra Sullivan, Ph.D.; Susan Carlson, Ph.D.
B. A., OKLAHOMA STATE UNIVERSITY, STILLWATER, OK
Major: Psychology, with honors; Minor: Philosophy
LICENSURE
Licensed as Psychologist in the state of Missouri (#2011033099)
POSITIONS
Assistant Professor (tenure track, research), Department of Psychology, University of Missouri—Kansas City (UMKC).
Postdoctoral Fellow, Mental Illness Research and Education Clinical Center (MIRECC), San Diego VA Healthcare System, San Diego, CA and Department of Psychiatry, University of California – San Diego (UCSD).
Mentors: Murray Stein, M.D., M.P.H. and Martin Paulus, M.D. Clinical Supervisor: Ariel Lang, Ph.D. and Sonya Norman, Ph.D.
Focus: Neuroimaging and decision-making in PTSD and anxiety disorders; empirically-based treatment of PTSD.
Psychology Intern, San Diego VA Healthcare System, San Diego, CA
Focus: Neuropsychology, cognitive rehabilitation for traumatic brain injury, empirically-supported treatment of posttraumatic stress disorder (PTSD) Supervisors: Amy Jak, Ph.D., Dawn Schiehser, Ph.D., Keylly Hughes, Ph.D., Steven Thorp, Ph.D., Dean Delis, Ph.D., Vincent Filoteo, Ph.D., Mark Bondi, Ph.D.
Therapist, Kansas City Center for Anxiety Treatment, Kansas City, KS
Supervisor: Lisa Hale, Ph.D. Focus: Obtained training and experience in implementing exposure-based therapies for anxiety disorders, including obsessive-compulsive disorder, social anxiety disorder, panic disorder, and generalized anxiety disorder.
Neuropsychometrician and research assistant, Hogland Brain Imaging Center, University of Kansas Medical Center, Kansas City, KS
Mentors: William Brooks, Ph.D. (PI) and Cary Savage, Ph.D. Focus: neuropsychological testing and data analyses for an R01-funded project examining proton magnetic resonance spectroscopy (H-MRS) predictors of recovery from traumatic brain injury.
Neuropsychometrician, VA Kansas City Healthcare System
Supervisor: Dean Skadeland, Psy.D. Focus: Neuropsychological assessment for variety of patient populations
Instructor, Brain and Pathology, University of Kansas, Lawrence, KS
Therapist, Health Psychology, University of Kansas Medical Center, KC, KS
Supervisors: Mike Rapoff, Ph.D., Martha Barnard, Ph.D., and Eve-Lynn Nelson, Ph.D., Robert Twillman, Ph.D., Bill Stiers, Ph.D. Rotations: Pediatrics, Telemedicine, Pain Management, and Neuropsychology
Therapist, Weight Management Program, University of Kansas, Lawrence, KC
Supervisor: James Grobe, Ph.D. Focus: provided psycho-education and group therapy as part of broader weight management research project.
2003-2004 Therapist, University of Kansas Psychological Clinic, University of Kansas, Lawrence, KS
Supervisors: Doug Witt, Ph. D., Cynthia Schnake, Ph. D., Raymond Higgins, Ph.D., and Sarah Kirk, Ph.D. Focus: building general psychotherapy skills; introduction to variety of therapy orientations
2002-2003 Neuropsychometrician, University of Kansas Medical Center; Kansas City, KS
Supervisor: Sally Frutiger, Ph. D. Focus: Neuropsychological assessment for variety of neurologic populations
Research Assistant, Neuropsychology Research Lab, University of Oklahoma Health Sciences Center, Oklahoma City, OK
Mentor: William Beatty, Ph.D. Responsibilities: Conducted assessment and assistant with data analysis and manuscript preparation for neuropsychological investigations of multiple sclerosis.
Research Assistant, Child Behavior Research Laboratory, Oklahoma State University (OSU)
Mentor: Maureen Sullivan, Ph.D. Focus: Recruitment of participants, data collection, and data entry for research projects examining child temperament and parenting styles.
HONORS AND AWARDS
Anxiety Disorders Association of America (ADAA) Career Development Award
American Psychological Foundation (APF) Graduate Research Scholarship
University of Kansas Madison and Lila Self Doctoral Fellowship
B. Kent Houston Award for Excellence in Health Psychology
American Psychological Association (APA) Dissertation Research Award
Outstanding Masters Thesis in the College of Arts and Sciences, University of Kansas
David Schulman Award for Excellence in Clinical Psychology, University of Kansas
Wentz Research Project Scholarship, Oklahoma State University, Stillwater, OK
Corre Anding Stegall Nation wide Leadership Award
Student Travel Award, Oklahoma Center for Neuroscience, Oklahoma City, OK
Top 10 Graduating Senior, Arts and Sciences, Oklahoma State University, Stillwater, OK
Top 2 Graduating Senior, Psychology Department, Oklahoma State University, Stillwater, OK
RESEARCH GRANTS
No Number PI: Robin Aupperle, Ph.D. 2012-2013 Frontiers: The Heartland Institute for Clinical and Translational Research
Pilot and Collaborative Studies Funding Program
Cognitive Training in PTSD: Effects on brain function and emotional processing. Submitted January 2012; decision to be announced March, 2012 Total costs: $30,000 CURRENT:
PT100018 PI: Amy Jak, Ph.D. 2011-2015 Department of Defense Congressionally Directed Medical Research Program Enhanced Cognitive Rehabilitation to Treat Comorbid TBI and PTSD. Role: Co-Investigator at time of funding (prior to leaving awarded institution for current position) Total costs: $2,162,552 COMPLETED:
No Number PI: Cary Savage, Ph.D. 2006-2007 University of Kansas Medical Center – Research Institute, FY2006 Clinical Pilot An fMRI Investigation of D-Cycloserine in Specific Phobia. Role: Co-PI
PROFESSIONAL MEMBERSHIPS
Society of Biological Psychiatry: 2009-present
Association for Behavioral and Cognitive Therapies: 2005-present
Anxiety Disorders Association of America: 2005-present
American Psychological Association: 2002-present
SERVICE/VOLUNTEER
Archives of General Psychiatry Behavioral Research and Therapy Biological Psychiatry Neuropharmacology Journal of Affective Disorders Behavioral Brain Research Depression and Anxiety Journal of the International Neuropsychological Society
Neuroimage PLoS ONE Psychoneuroendocrinology International Society for Traumatic Stress Studies Conference Abstracts
CLINICAL PRESENTATIONS Aupperle, R.L. (2007, September). Brain Structure and Function. Presented to the National Alliance of Mental Illness
Aupperle, R.L., Bui, T.G. (2007, April). Assessment and Treatment of Obsessive-Compulsive Disorder. Presented to the
Greater Kansas City Psychological Association (GKCPA), Kansas City, MO.
Aupperle, R.L. (2005, June). Exposure Therapy for Specific Phobia. Presented as part of a larger workshop related to the
assessment and treatment of anxiety disorders, conducted by the Kansas City Center for Anxiety Treatment clinical team (led by Dr. Lisa Hale). Presented to the Johnson County Community Mental Health Center (JCMH), Overland Park, KS.
ORAL RESEARCH PRESENTATIONS Aupperle, R.L., Allard, C.B., Grimes, E.M., Simmons, A.N., Flagan, T., Cissell, C.H., Thorp, S.R., Norman, S.B.,
Paulus, M.P., Stein, M.B. (submitted for presentation in April, 2012). Neural System Function Predicts Response to Cognitive Trauma Therapy in Women with Domestic Violence-Related PTSD. Part of larger symposium submitted for presentation at the Anxiety Disorders Association of America (ADAA) in Arlington, Virginia.
Aupperle, R.L., Allard, C.B., Grimes, E.M., Simmons, A.N., Flagan, T., Cissell, C.H., Thorp, S.R., Norman, S.B.,
Paulus, M.P., Stein, M.B. (2011, November). Executive Function in PTSD: Relationship to Neural Responses during Affective Anticipation. Part of larger symposium for presentation at the International Society for Traumatic Stress Studies in Baltimore, MD.
Aupperle, RL, Ramsawh, H., Flagan, T., Sullivan, S., Fonzo, G., Letamendi, A., Simmons, A.N., Paulus, M.P., Stein,
M.B. (2011, November). Neural Substrates of Anticipatory Processing in Generalized Anxiety and Panic Disorder: Predictors of Cognitive Behavioral Therapy Treatment Response. Part of larger symposium for presentation at the Association for Behavioral and Cognitive Therapies (ABCT) in Toronto, Canada.
Paulus, M.P., Aupperle, R.L., Flagan, T., Jain, K., Simmons, A.N., Stein, M.B. (2011, May). Individuals With Combat- related PTSD Show Attenuated Error Processing In A Simple Decision-making Paradigm. Presented at the Society of Biological Psychiatry annual conference, San Francisco, CA.
Aupperle, R.L., Sullivan, S., Melrose, A.J., Paulus, M.P., Stein, M.B. (2011, April). Reverse Translation of Approach- Avoidance Conflict Models for Human Research. Presented at the University of California – San Diego Department of Psychiatry annual junior faculty and postdoctoral fellow research symposium, La Jolla, CA.
Aupperle, R.L., Sullivan, S.R., Melrose, J., Stein, M.B., Paulus, M,P. (2011, March). Reverse Translation of Approach- Avoidance Conflict Models for Human Research. Presented at the Anxiety Disorders Association of America (ADAA) annual conference, New Orleans, LA.
Aupperle, R.L., Allard, C.B., Grimes, E.M., Simmons, A.N., Flagan, T., Cissell, C.H., Thorp, S.R., Norman, S.B.,
Paulus, M.P., Stein, M.B. (2010, March). Neural Systems Dysfunction during Anticipation in Women with Posttraumatic Stress Disorder Related to Intimate Partner Violence. Presented at the Anxiety Disorders Association of America (ADAA) annual conference, Baltimore, MD.
Aupperle, R.L., Hale, L.R., Chambers, R.J., Cain, S.E, Barth, F.X., Sharp, S.C., Denney, D.R., & Savage, C.R. (2008,
May). An fMRI investigation of D-cycloserine and Symptom Provocation in Spider Phobia. Presented at the Society of Biological Psychiatry (SOBP) annual conference in Washington, D.C.
Aupperle, R.L., Hale, L.R., Denney, D.R., Chambers, R.J., Cain, S.E, Barth, F.X., Sharp, S.C., Savage, C.R. (2007,
March). An fMRI study investigating the effects of D-cycloserine on brain activations during verbal memory recognition. Presented at Neuroscience (SfN) annual conference in San Diego, CA.
Aupperle, R.L., Savage, C.R. (2007, March). Repeated Symptom Provocation in Spider Phobia: D-Cycloserine, Preliminary Results. Presented at the Social Neuroscience Winter Institute (SNWI) in Bethel, ME.
POSTER RESEARCH PRESENTATIONS
Aupperle, R.L., Allard, C.B., Grimes, E.M., Simmons, A.N., Flagan, T., Cissell, C.H., Thorp, S.R., Norman, S.B.,
Paulus, M.P., Stein, M.B. (2011, December). Predictors and Consequences of Cognitive Therapy for PTSD: Neural Responses to Emotional Anticipation. To be presented at the American College of Neuropsychopharmacology (ACNP) annual conference, Waikaloa Beach, Hawaii.
Flagan, T.M., Aupperle, R.L., Simmons, A.N., Paulus, M.P., Stein, M.B. (2011, May). Trait Anxiety influences Neural Systems underlying Risky Decision Making. Presented at the Society of Biological Psychiatry annual conference, San Francisco, CA.
McCurdy, D.P., Aupperle, R.L., Flagan, T.M., Grenesko-Stevens, E., Wagner, A., Paulus, M.P., Kaye, W.H. (2011,
May). Neurobiology of Eating Disorders: An fMRI Investigation of Tastes to Sucrose. Presented at the Society of Biological Psychiatry annual conference, San Francisco, CA.
Aupperle, R.L., Allard, C.B., Grimes, E.M., Simmons, A.N., Flagan, T., Cissell, C.H., Thorp, S.R., Norman, S.B.,
Paulus, M.P., Stein, M.B. (2010, December). Unique influence of PTSD symptom clusters on Neural Activations during Anticipatory Processing. Presented at the American College of Neuropsychopharmacology (ACNP) annual conference, Miami Beach, FL.
Aupperle, R.L., Ramsawh, H., Flagan, T., Sullivan, S., Fonzo, G., Letamendi, A., Simmons, A.N., Paulus, M.P., Stein,
M.B. (2010, November). Generalized Anxiety Disorder, Social Anxiety Disorder, and Panic Disorder: Common and Unique Neural Substrates of Anticipation. Presented at the Society for Neuroscience (SfN) annual conference, San Diego, CA.
Flagan, T.M., Aupperle, R.L., Gillis, K., Simmons, A.N., Swain J.L., Paulus, M.P. (2010, November). Attenuated Insula Activation during Non-hypercapnic Breathing Restriction: Evidence for More Eefficient Neural Processing in Elite Performers in Extreme Environments. Society for Neuroscience Annual Meeting, San Diego, CA.
Aupperle, R.L., Ravindran, L., Tankersley, D., Flagan, T., Simmons, A.N., Stein, M.B., Paulus, M.P. (2010, May). Neural Effects of Pregabalin in Healthy Controls during Anticipation. Presented at the Society of Biological Psychiatry (SOBP) annual conference, New Orleans, LA.
Nelson, C.A., Hale L., Aupperle, R.L.; Hamilton, N.A.; Savage, C.R. (2009, November). Memory Confidence, Source Memory Accuracy, and Obsessive-Compulsive Symptoms. Presented at the Association of Behavioral and Cognitive Therapies (ABCT) annual conference in New York.
Nelson, C.A., Hale L., Aupperle, R.L., Hamilton, N.A., Savage, C.R. (2008, November). Organizational Strategies and Memory in Individuals with Subclinical Obsessive-Compulsive Symptoms. Presented at the Association of Behavioral and Cognitive Therapies (ABCT) in Orlando, FL, November, 2008.
Aupperle, R.L., Hale, L.R., Nelson. C.R., Chambers, R.J., Cain, S.E, Barth, F.X., Sharp, S.C., Hall, S.B., Denney, D.R.,
Savage, C.R. (2007, March). A double-blind, placebo-controlled, fMRI investigation of D-cycloserine and Symptom Provocation in Spider Phobia: Preliminary results. Presented at the Anxiety Disorders Association of America (ADAA) annual conference in St. Louis, MO.
Brooks, W.M., Hall, S.B., Lierman, J.L., Schmitt, A.L., Ladeseich, L.R., Malone, T.M., Aupperle, R.L., Savage, C.R.
(2006, May). Magnetic Resonance Spectroscopic Imaging is Sensitive to Severity in Traumatic Brain Injury. Presented at the International Society for Magnetic Resonance (ISMRM) in Medicine, Seattle, WA.
Aupperle, R.L., Savage, C.R,, Lierman, J.A., Schmitt, A., Ladesich, L., Varghese, G., Malone, T.M., Hall, S.B., Brooks,
W.M. (2005, November). Magnetic Resonance Spectroscopic Imaging and Psychological Symptoms 3 months Post-Traumatic Brain Injury. Presented at Neuroscience (SfN) conference, Washington, D.C.
Aupperle, R.L., Denney, D., Lynch, S. (2005, September). Omega-3 Fatty Acid Levels in Multiple Sclerosis: Correlation of Diet, Disability, and Depression. Presented at the annual convention of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) and the American Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS), Thessalonika, Greece.
Aupperle, R.L., Savage, C.R,, Lierman, J.A., Schmitt, A., Ladesich, L., Varghese, G., Malone, T.M., Hall, S.B., Brooks,
W.M. (2004, April). Proton Magnetic Resonance Spectroscopy at 3-tesla and Cognitive Function in Traumatic Brain Injury. Presented at the Kansas City Life Sciences Institute (KCLSI) Conference, Kansas City, KS.
Gontkovsky, S.T., Aupperle, R.L., Shelton, F., Beatty, W.W. (2002, February). Relationship between Depression and Attentional/Memory Processes in Multiple Sclerosis. Presented at the American Neuropsychiatric Association (ANPA), 2002.
Gontkovsky S, Beatty W, McDonald N, Aupperle R (2002). Factors Affecting the Employment Status of Patients with Multiple Sclerosis. Archives of Clinical Neuropsychology, 17: 723. Presented at the National Academy of Neuropsychology.
Aupperle, R.L., Beatty, W.W., Shelton, F., & Gontvoskey, S. (2002, February). Three Screening Batteries to Detect Cognitive Impairment in Multiple Sclerosis. Presented at the International Neuropsychological (INS) Conference, Toronto, Canada.
PUBLICATIONS
Aupperle, R.L., Allard, C.B., Grimes, E.M., Simmons, A.N., Flagan, T., Cissell, C.H., Thorp, S.R., Norman, S.B.,
Paulus, M.P., Stein, M.B. (in preparation). Predictors and consequences of cognitive therapy for PTSD: Neural responses to emotional anticipation. Aupperle, R.L., Ramsawh, H., Flagan, T., Sullivan, S., Fonzo, G., Letamendi, A., Simmons, A.N., Paulus, M.P., Stein,
M.B. (in preparation). Generalized anxiety disorder, social anxiety disorder, and panic disorder: Common and unique neural substrates of anticipation.
Aupperle, R.L., Connely, C., Jain, K., Paulus, M.P. (in preparation). Relationship between voxel-based gray matter
volume, deployment experiences and PTSD symptoms.
Flagan, T.M., Aupperle, R.L., Simmons, A.N., Paulus, M.P., Stein, M.B. (in preparation). Trait anxiety influences neural
systems underlying risky decision making.
Mano, Q.R., Brown, G. G., Bolden, K., Aupperle, R., Sullivan, S., Paulus, M.P., Stein, M.B. (under review). Curvilinear
relationship between phonological working memory load and socioemotional modulation.
Aupperle, R.L., Tankersley, D., Ravindran, L., Stein, N.R., Stein, M.B., Paulus, M.P. (under review). Pregabalin effects
on amygdala and insula activation during emotional face processing.
Aupperle, R.L., Allard, C.B., Grimes, E.M., Simmons, A.N., Flagan, T., Cissell, C.H., Thorp, S.R., Norman, S.B.,
Paulus, M.P., Stein, M.B. (in press). Neural systems dysfunction during anticipation in women with posttraumatic stress disorder related to intimate partner violence. Archives of General Psychiatry. Aupperle, R.L., Sullivan, S.R., Melrose, J., Stein, M.B., Paulus, M,P. (2011). A reverse translational approach to
quantify approach-avoidance conflict in humans. Behavioural Brain Research, 225(2), 455-463. doi:10.1016/j.bbr.2011.08.003 Aupperle, R.L., Melrose, J., Paulus, M.P (2011). Executive function and PTSD: Disengaging from trauma. Neuropharmacology. doi:10.1016/j.neuropharm.2011.02.008
Aupperle, R.L., Lakshmi, R., Tankersley, D., Flagan, T., Simmons, A.N., Stein, M.S., Paulus, M.P. (2011). Pregabalin
influences amygdala and insula activation during anticipation. Neuropsychopharmacology36(7), 1466–1477.doi:10.1038/npp.2011.32
Aupperle, R.L., Paulus, M.P. (2010). Neural systems underlying approach and avoidance in anxiety disorders. Review. Dialogues of Clinical Neuroscience, 12(4): 517-531. Aupperle, R.L., Hale, L.R., Chambers, R.J., Cain, S.E, Barth, F.X., Sharp, S.C., Hall, S.B., Denney, D.R., Savage, C.R.
(2009). An fMRI study examining effects of acute D-cycloserine during symptom provocation in spider phobia. CNS Spectrums, 14:556-571.
Aupperle, R.L., Denney, D.R., Lynch, S.G. (2008). Omega-3 fatty acids and multiple sclerosis: Relationship to
depression. Journal of Behavioral Medicine, 31: 127-135. doi: 10.1007/s10865-007-9139-y Aupperle, R., Beatty, W., Shelton, F., Gontvoskey, S. (2002). Three screening batteries to detect cognitive impairment in
Multiple Sclerosis. Multiple Sclerosis, 8: 382-389. doi: 10.1191/1352458502ms832oa.
Beatty, W., Aupperle, R. (2002). Sex differences in cognitive impairment in Multiple Sclerosis. Clinical Neuropsychologist, 16: 472-480. http://dx.doi.org/10.1076/clin.16.4.472.13904
MILPRIT : Mining Interval Logic Patterns with Regular Expression Constraints Sandra de Amo 1 , Arnaud Giacometti 2 , Magno Soares Santana 1 1Faculdade de Computac¸˜ao – Universidade Federal de Uberlˆandia (UFU)[email protected], [email protected], [email protected] Abstract. Most methods for temporal pattern mining assume that time is pon- tual, that is, represented by points in a stra
The “Reality Check” is a policy review process aiming to gather insights from top domestic and international analysts, practitioners, diplomats and policy-makers working in and on the EaP countries, with the ambition to discuss these behind closed doors. Under the aegis of the Lithuanian EU Presidency the first such a review was the Belarus Reality Check, held in Vilnius, Lithuania in The