Het is echter wel schadelijk om overmatig te alcohol te drinken, zeker als u een infectie heeft. Dit komt de infectie eerder verergerd door het gebruik van alcohol antibiotica en ibuprofen samen Doorgaans worden ze voorgeschreven bij bacteriële infecties die om de één of andere reden niet uit zichzelf over gaan; ze doden dan de bacteriën.
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SAFETY DATA SHEET _____________________________________________________________________________ 1. IDENTIFICATION OF THE SUBSTANCE/PREPARATION AND OF THE COMPANY/UNDERTAKING Product Name: Gallic Acid Monohydrate Catalog Number: 73801 SDS Number: M00253 Chemical Name: 3,4,5-Trihydroxybenzoic Acid Monohydrate Chemical Formula: C7H6O5 · H2O Chemical Family: Organic Acid Use of the substance/preparation: Laboratory Reagent CAS No.: 5995-86-8 Hazard: May cause irritation. Safety Data Sheet written according to Regulation (EU) No. 1907/2006 (REACH): Date of MSDS Preparation: Day: 15 Month: October Year: 2009 Additional Emergency Response Numbers: Additional European Addresses: Austria: Belgium: Denmark: France: Ireland: Italy: Netherlands: Spain: Sweden: Switzerland: United Kingdom: _____________________________________________________________________________ 2. HAZARDS IDENTIFICATION Emergency Overview: Appearance: White to light yellow crystals Odor: None EU Symbols: Xi - IRRITATING R PHRASES: R 36/37/38: Irritating to eyes, respiratory system and skin. Protective Equipment: Potential Health Effects: Eye Contact (EC): Causes irritation Skin Contact (EC): Causes irritation Skin Absorption (EC): None Reported Target Organs (SA E): None Reported Ingestion (EC): May cause: weakness convulsions body temperature reduction Target Organs (Ing E): None Reported Inhalation: Causes: respiratory tract irritation Target Organs (Inh E): None Reported Medical Conditions Aggravated: Allergies or sensitivity to aspirin or salicylates. Chronic Effects: None reported Cancer / Reproductive Toxicity Information: IARC Listed: No Additional Cancer / Reproductive Toxicity Information: an experimental mutagen. an experimental teratogen. Toxicologically Synergistic Products: None reported _____________________________________________________________________________ 3. COMPOSITION / INFORMATION ON INGREDIENTS Gallic Acid EEC Number: 2057499 CAS No.: 5995-86-8 Percent Range: 100,0 Percent Range Units: weight / weight Ingredient EEC Symbol: Xi - IRRITATING Ingredient R phrase(s): R 36/37/38 TLV: Not established PEL: Not established EU Occupational Exposure Limits: 3 mg/m3, Inhalable dust _____________________________________________________________________________ 4. FIRST AID MEASURES Eye Contact: Immediately flush eyes with water for 15 minutes. Call physician. Skin Contact (First Aid): Wash skin with soap and plenty of water. Call physician if irritation develops. Ingestion (First Aid): Give large quantities of water. Call physician immediately. Inhalation: Remove to fresh air. _____________________________________________________________________________ 5. FIRE FIGHTING MEASURES Flammable Properties: Can burn in fire, releasing toxic vapors. Hazardous Combustion Products: Toxic fumes of: carbon monoxide, carbon dioxide. Fire / Explosion Hazards: None reported Static Discharge: None reported. Mechanical Impact: None reported Extinguishing Media: Use media appropriate to surrounding fire conditions Extinguishing Media NOT To Be Used: Not applicable Fire Fighting Instruction: As in any fire, wear self-contained breathing apparatus pressure-demand and full protective gear. _____________________________________________________________________________ 6. ACCIDENTAL RELEASE MEASURES Spill Response Notice: Only persons properly qualified to respond to an emergency involving hazardous substances should respond to a spill involving chemicals. See Section 13, Special Instructions for disposal assistance. Containment Technique: Stop spilled material from being released to the environment. Clean-up Technique: Scoop up spilled material into a large beaker and dissolve with water. Adjust to a pH between 6 and 9 with an alkali, such as soda ash or sodium bicarbonate. Flush reacted material to the drain with a large excess of water. Decontaminate the area of the spill with a soap solution. Evacuation Procedure: Evacuate as needed to perform spill clean-up. If conditions warrant, increase the size of the evacuation. _____________________________________________________________________________ 7. HANDLING AND STORAGE Handling: Avoid contact with eyes skin Do not breathe dust. Wash thoroughly after handling. Maintain general industrial hygiene practices when using this product. Storage: Keep away from: oxidizers ammonia Special Packaging Instructions: Not applicable Use of the substance/preparation: Laboratory Reagent _____________________________________________________________________________ 8. EXPOSURE CONTROLS / PROTECTIVE EQUIPMENT Engineering Controls: Have an eyewash station nearby. Maintain general industrial hygiene practices when using this product. Personal Protective Equipment: Eye Protection: safety glasses with top and side shields Skin / Hand Protection: disposable latex gloves Inhalation Protection: dust / mist mask adequate ventilation Precautionary Measures: Avoid contact with: eyes skin Do not breathe: dust Wash thoroughly after handling. TLV: Not established PEL: Not established EU Occupational Exposure Limits: 3 mg/m3, Inhalable dust _____________________________________________________________________________ 9. PHYSICAL / CHEMICAL PROPERTIES Appearance: White to light yellow crystals Physical State: Solid Odor: None pH: 5% solution = 2,8 Vapor Pressure: Not applicable Vapor Density (air = 1): Not applicable Boiling Point: Not applicable Melting Point: loses H2O @ 100-120°C; decomposes @ 225-250°C Flash Point: Not applicable Method: Not applicable Autoignition Temperature: Not available Flammability Limits: Lower Explosion Limits: Not applicable Upper Explosion Limits: Not applicable Specific Gravity (water = 1): 1,694 Evaporation Rate (water = 1): Not applicable Volatile Organic Compounds Content: Not available Partition Coefficient (n-octanol / water): Not available Solubility: Water: 1 gm in 87 ml H2O; 1 gm in 3 ml boiling H2O Acid: Not available Other: Insoluble in benzene, chloroform. Soluble in acetone, alcohol. Metal Corrosivity: Steel: Not determined Aluminum: 0,011 in/yr (0,279 mm/yr). _____________________________________________________________________________ 10. STABILITY / REACTIVITY Chemical Stability: Stable when stored under proper conditions. Conditions to Avoid: Heating to decomposition. Reactivity / Incompatibility: Incompatible with: oxidizers ammonia carbonates Hazardous Decomposition: Heating to decomposition releases toxic fumes of carbon monoxide and carbon dioxide. Hazardous Polymerization: Will not occur. _____________________________________________________________________________ 11. TOXICOLOGICAL INFORMATION Product Toxicological Data: LD50: Oral rabbit LD50 = 5 gram/kg LC50: Not available Dermal Toxicity Data: Not available Skin and Eye Irritation Data: Not available Mutation Data: Cytogenetic analysis - mouse - intraperitoneal - 100 µmol/kg; Cytogenetic analysis - hamster - ovary - 50 mg/l Reproductive Effects Data: Subcutaneous rat TDLo = 5 mg/kg - Maternal Effects - ovaries/fallopian tubes -- Ingredient Toxicological Data: Not applicable IARC Listed: No _____________________________________________________________________________ 12. ECOLOGICAL INFORMATION Product Ecological Information: No ecological information available for this product. Ingredient Ecological Information: Not applicable _____________________________________________________________________________ 13. DISPOSAL CONSIDERATIONS NOTICE (Disposal): These disposal guidelines are based on federal regulations and may be superseded by more stringent state or local requirements. Please consult your local environmental regulators for more information. In Europe: Chemical and analysis solutions must be disposed of in compliance with the respective national regulations. Product packaging must be disposed of in compliance with the country-specific regulations or must be passed to a packaging return system. _____________________________________________________________________________ 14. TRANSPORT INFORMATION I.C.A.O.: I.C.A.O. Proper Shipping Name: Not Currently Regulated -- ICAO Hazard Class: NA ICAO Subsidiary Risk: NA ICAO UN/ID Number: NA ICAO Packing Group: NA I.M.O.: I.M.O. Proper Shipping Name: Not Currently Regulated -- I.M.O. Hazard Class: NA I.M.O. Subsidiary Risk: NA I.M.O. UN Number: NA I.M.O. Packing Group: NA A.D.R.: A.D.R. Proper Shipping Name: Not Currently Regulated -- A.D.R Hazard Class: NA A.D.R. Subsidiary Risk: NA A.D.R. UN-Number:: NA A.D.R. Packing Group: NA Additional Information: There is a possibility that this product could be contained in a reagent set or kit composed of various compatible dangerous goods. If the item is NOT in a set or kit, the classification given above applies. If the item IS part of a set or kit, the classification would change to the following: UN3316 Chemical Kit, Class 9, PG II or III. If the item is not regulated, the Chemical Kit classification does not apply. _____________________________________________________________________________ 15. REGULATORY INFORMATION National Inventories: EEC Inventory Status: EINECS Listed: Yes EEC Number: 2057499 EEC LABEL COPY: EU Symbols: Xi - IRRITATING R PHRASES: R 36/37/38: Irritating to eyes, respiratory system and skin. S PHRASES: S 26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36: Wear suitable protective clothing. Ingredients: Gallic Acid; _____________________________________________________________________________ 16. OTHER INFORMATION References: 29 CFR 1900 - 1910 (Code of Federal Regulations - Labor). Air Contaminants, Federal Register, Vol. 54, No. 12. Thursday, January 19, 1989. pp. 2332-2983. TLV's Threshold Limit Values and Biological Exposure Indices for 1992-1993. American Conference of Governmental Industrial Hygienists, 1992. Sax, N. Irving. Dangerous Properties of Industrial Materials, 7th Ed. New York: Van Nostrand Reinhold Co., 1989. Vendor Information. Technical Judgment. Gosselin, R. E. et al. Clinical Toxicology of Commercial Products, 5th Ed. Baltimore: The Williams and Wilkins Co., 1984. The Merck Index, 11th Ed. Rahway, New Jersey: Merck and Co., Inc., 1989. Use of the substance/preparation: Laboratory Reagent Revision Summary: Updates in Section(s) 14, _____________________________________________________________________________ Legend: USER RESPONSIBILITY: Each user should read and understand this information and incorporate it in individual site safety programs in accordance with applicable hazard communication standards and regulations. THE INFORMATION CONTAINED HEREIN IS BASED ON DATA CONSIDERED TO BE ACCURATE. HOWEVER, NO WARRANTY IS EXPRESSED OR IMPLIED REGARDING THE ACCURACY OF THESE DATA OR THE RESULTS TO BE OBTAINED FROM THE USE THEREOF. HACH COMPANY 2009
RAe Rudolph ● Albrecht-Dürer-Platz 4 ● 90403 Nürnberg Juristische Grundlagen der Strafbarkeit der Frauenärzte wegen Einkauf Medikamente bei SigmaGyn Der Straftatbestand des § 96 Nr. 5 AMG ist lediglich dann erfüllt, wenn es sich bei den verfahrensgegenständlichen Medikamenten um solche handelt, denen entgegen § 21 I AMG die erforderliche Zulassung fehlte. Den Nachweis, dass die durc
Prof. Dr. Rüdiger Hehlmann Director III. Medizinische Klinik, Mannheim III. Medizinische Klinik Medizinische Fakultät Mannheim der Universität Heidelberg Wiesbadener Str. 7-11 68305 Mannheim 0621 383 4115 (phone) 0621 383 4201 (fax) [email protected] SCIENTIFIC VITA Assistant, Max Planck Institute for Biochemistry, Munich Research Fellow, University of Rochester, N